Review



early passage normal human female colon fibroblast ccd 18co cell line  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 97
      Buy from Supplier

    Structured Review

    ATCC early passage normal human female colon fibroblast ccd 18co cell line
    Early Passage Normal Human Female Colon Fibroblast Ccd 18co Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 976 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pm42140904-59-1-13?v=ATCC
    Average 97 stars, based on 976 article reviews
    early passage normal human female colon fibroblast ccd 18co cell line - by Bioz Stars, 2026-07
    97/100 stars

    Images



    Similar Products

    early passage normal human female colon fibroblast ccd 18co cell line  (ATCC)
    97
    ATCC early passage normal human female colon fibroblast ccd 18co cell line
    Early Passage Normal Human Female Colon Fibroblast Ccd 18co Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pm42140904-59-1-13?v=ATCC
    Average 97 stars, based on 1 article reviews
    early passage normal human female colon fibroblast ccd 18co cell line - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    colon fibroblast line ccd 18co  (ATCC)
    97
    ATCC colon fibroblast line ccd 18co
    Colon Fibroblast Line Ccd 18co, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pm42021323-90-17-25?v=ATCC
    Average 97 stars, based on 1 article reviews
    colon fibroblast line ccd 18co - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    non tumorigenic colon fibroblast line ccd 18co  (ATCC)
    97
    ATCC non tumorigenic colon fibroblast line ccd 18co
    Non Tumorigenic Colon Fibroblast Line Ccd 18co, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pm41673274-40-12-23?v=ATCC
    Average 97 stars, based on 1 article reviews
    non tumorigenic colon fibroblast line ccd 18co - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    colonic fibroblast cell line  (ATCC)
    97
    ATCC colonic fibroblast cell line
    Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in <t>CCD-18Co</t> fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three <t>fibroblast</t> conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.
    Colonic Fibroblast Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pmc12832729-72-6-15?v=ATCC
    Average 97 stars, based on 1 article reviews
    colonic fibroblast cell line - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    human colon fibroblast cell line ccd 18co  (ATCC)
    97
    ATCC human colon fibroblast cell line ccd 18co
    Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in <t>CCD-18Co</t> fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three <t>fibroblast</t> conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.
    Human Colon Fibroblast Cell Line Ccd 18co, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pmc12501291-96-1-22?v=ATCC
    Average 97 stars, based on 1 article reviews
    human colon fibroblast cell line ccd 18co - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    ccd 18co human colon cell line fibroblast  (ATCC)
    97
    ATCC ccd 18co human colon cell line fibroblast
    Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in <t>CCD-18Co</t> fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three <t>fibroblast</t> conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.
    Ccd 18co Human Colon Cell Line Fibroblast, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pm39978509-115-0-9?v=ATCC
    Average 97 stars, based on 1 article reviews
    ccd 18co human colon cell line fibroblast - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    normal colon fibroblast cell line  (ATCC)
    97
    ATCC normal colon fibroblast cell line
    Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in <t>CCD-18Co</t> fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three <t>fibroblast</t> conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.
    Normal Colon Fibroblast Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/colon+fibroblast+line+ccd+18co/pmc11814099-147-13-38?v=ATCC
    Average 97 stars, based on 1 article reviews
    normal colon fibroblast cell line - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier

    Image Search Results


    Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in CCD-18Co fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three fibroblast conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.

    Journal: Frontiers in Immunology

    Article Title: From multi-omics to functional validation: the PTMRS stratifies TME and positions PDGFRB in CRC biology

    doi: 10.3389/fimmu.2025.1728291

    Figure Lengend Snippet: Impact of PDGFRb perturbation within tumor-associated fibroblasts on CRC cell phenotypes. (A) Western blots of t-PDGFRb and p-PDGFRb in CCD-18Co fibroblasts treated with vehicle (Veh), PDGF-BB, or PDGF-BB plus SUN. b-actin serves as a loading control. (B) Quantification of the p-PDGFRb/t-PDGFRb ratio relative to the Veh group. (C) Representative EdU staining of HCT116 cells cultured with CM from the three fibroblast conditions (Veh-CM, PDGF-BB-CM, SUN-CM). EdU (green), DAPI (blue), merged images as indicated. (D) Relative EdU labeling index in HCT116 cells. (E, F) CCK-8 assays showing relative cell viability of HCT116 (E) and DLD-1 (F) cells after 48 h exposure to Veh-CM, PDGF-BB-CM, or SUN-CM. (G) Representative Transwell images of migrated HCT116 and DLD-1 cells under the indicated CM conditions. (H, I) Quantification of migrated HCT116 (H) and DLD-1 (I) cells per 10× field. (J) Violin plots showing concentrations of CCL5, CXCL12, IL-6, IL-10, and TGF-b1 in fibroblast CM measured by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs Veh group; ns, no significant difference. Abbreviations: Veh, vehicle; SUN, sunitinib; CM, conditioned medium; PDGF-BB, the BB homodimer of platelet-derived growth factor.

    Article Snippet: Human CRC cell line HCT116 and colonic fibroblast cell line (CCD-18Co) were obtained from the American Type Culture Collection (ATCC) and cultured in Dulbecco’s Modified Eagle Medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin at 37 °C in a 5% CO 2 humidified incubator.

    Techniques: Western Blot, Control, Staining, Cell Culture, Labeling, CCK-8 Assay, Enzyme-linked Immunosorbent Assay, Derivative Assay